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Home Lifestyle Health

The Science Behind Mounjaro Weight Loss: How It Works

Do not take this medication if you have had thyroid C-cell tumors or Multiple Endocrine Neoplasia syndrome type two. Doing so could increase your risk of pancreatitis.

Musasi Isaac by Musasi Isaac
September 20, 2023
in Health, Lifestyle
Reading Time: 7 mins read
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Mounjaro is an injectable medication administered subcutaneously once every week at any time during the day or night.

CUPERTINO, CALIFORNIA | NOW THEN DIGITAL — Mounjaro is an innovative medication designed to help diabetics manage weight and improve blood sugar control simultaneously. It works by increasing your body’s sensitivity to insulin and decreasing your blood sugar levels, ultimately improving both weight loss and control of blood sugar.

Tirzepatide (Mounjaro) works by stimulating GIP and glucagon-like peptide-1 receptors to suppress appetite. According to clinical trials, participants taking tirzepatide experienced significant weight loss while experiencing improvements in blood sugar.

At times, Mounjaro can cause allergic reactions in some individuals.

mounjaro vs ozempic

Mounjaro should not be taken if you are allergic to any of its ingredients or can anticipate experiencing adverse reactions from taking it. Because Mounjaro may worsen diabetic retinopathy, your physician will likely suggest visiting an ophthalmologist should any vision changes arise from its use. Since Mounjaro is relatively new medication, some medical insurance providers require prior authorization before coverage; the manufacturer provides savings cards as a means of offsetting costs; your Calibrate doctor can help ensure you obtain all coverage options necessary for coverage when needed.

General Information

Mounjaro from Eli Lilly was granted FDA approval as a dual GIP/GLP-1 receptor agonist to treat type-2 diabetes; however, it has also been used off-label for weight loss purposes. Mounjaro should be combined with lifestyle modifications including diet and exercise for maximum benefits.

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Mounjaro should be administered subcutaneously (subdermally) once weekly at any time of day in your stomach, thigh, or upper arm at any time. Studies conducted on participants who took Mounjaro saw their average A1C drops between 1.8%-2.4% during studies with higher doses achieving better results.

While not FDA-approved for weight loss specifically, Mounjaro has been proven to help individuals reduce weight alongside diet and exercise – participants in SURPASS clinical trials that led to Mounjaro approval reported losing an average weight loss between 5.5 kg (12 pounds) to 11kg (25 pounds).

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Mounjaro is a GLP-1 medication and may cause side effects including nausea, vomiting, diarrhea and abdominal pain. These usually subside over time but it’s important to monitor for signs of serious adverse reactions.

Mounjaro prices will depend on several factors, including your health insurance plan, pharmacy of choice and location. It’s essential that you are aware of your costs prior to enrolling in any programs; commercial prescription coverage usually offers lower medication prices.

Some individuals who take Mounjaro with other medications may experience more serious side effects, including heart attack or stroke. This phenomenon is known as drug-drug interactions; therefore it is essential that all prescription and nonprescription drugs, vitamins, minerals and herbs you are currently taking be reported to your FORM physician so they can select an optimal dose of Mounjaro for you.

Features

Mounjaro side effects

Mounjaro (Tirzepatide) has received much media coverage due to its success in clinical trials where overweight and obese participants lost between 5-22.5% of their bodyweight. Yet there remains considerable concern over any possible risks this medication might present.

Mounjaro weight loss program relies on an injectable prescription medication called Tirzepatide from Eli Lilly and Company that has been FDA-approved to improve blood sugar (glucose) in adults with type 2 diabetes and is used alongside diet and exercise to facilitate weight loss.

This medication works by stimulating both glucose-dependent insulinotropic polypeptide (GIP) receptors and glucagon-like peptide-1 receptors to decrease how much food you eat and increase energy used by your body, leading to weight loss. Furthermore, this increases how well insulin responds within your system, further decreasing blood sugar.

Your doctor will inject subdermally in your stomach, thigh, or upper arm. Injections can be given any time of the day; however it’s ideal to give them soon after eating or at least snacking to ensure the medicine absorbs properly.

Also note that injections should not occur twice every week in the same place; you should try switching sites each week instead.

Benefits

Mounjaro (tirzepatide) is an injectable prescription drug intended to control blood sugar (glucose) levels in those living with type 2 diabetes. The medication works by decreasing food consumption and slowing how quickly meals travel through your digestive tract, thereby making you feel full faster.

Mounjaro works by activating GIP receptors (glycodependent insulinotropic polypeptide) and GLP-1 receptors (glucagon-like peptide 1) which are natural incretin hormones.

Studies showed that those taking Mounjaro alongside a reduced-calorie diet and exercise saw greater weight loss than those not taking it, with prediabetics experiencing decreased insulin use due to improved blood sugar levels and less need for treatment.

Mounjaro belongs to a new class of medications known as GLP-1 receptor agonists which have proven successful at aiding weight loss for adults with type 2 diabetes.

As important, however, is to remember that not everyone responds the same to these medications. Some may experience side effects like nausea and vomiting while for others they cause stomach pain or indigestion.

Some individuals may even experience changes in vision while gallbladder issues have been noted among a small percentage of patients.

Current FDA label for weight loss medication does not approve for off-label use for weight loss; therefore, physicians prescribe it off-label when used to assist weight loss.

If you want to try taking this drug off-label to aid in weight loss, Calibrate or Ro Body can connect you with licensed telehealth professionals who will evaluate your health needs and assess if this medicine would benefit you; they will also issue an electronic prescription and direct you towards a pharmacy where they will supply their medication.

Overall Approach

Mounjaro weight loss

Mounjaro (tirzepatide), produced by Eli Lilly and FDA-approved as part of its GLP-1 agonist class of drugs, joins Ozempic and Wegovy as one of several injectable medications approved for treating type-2 diabetes along with diet and exercise.

As with its predecessors, this treatment may also promote weight loss without an FDA approval, though weight loss results have yet to be seen with Mounjaro use alone.

Ozempic and Wegovy both derive from semaglutide; Mounjaro stands out by using a dual agonist that acts on both GLP-1 receptors as well as GIP receptors to stimulate hormones that suppress appetite, providing a stronger overall effect and distinguishing it from its competitors in clinical trials.

However, this dual agonist approach has also been linked with more severe gastrointestinal side effects, including diarrhea, nausea and abdominal pain. Furthermore, no clinical testing has been conducted in patients with severe GI conditions; hence increasing their risk of pancreatitis.

Mounjaro can be expensive, making it difficult for many to afford due to limited coverage from insurance and Medicare plans. Mounjaro comes with a warning box warning of thyroid C-cell tumors in rats; its effect on human thyroid cancer remains uncertain.

While the side effects may be uncomfortable, they usually clear up after several days or weeks. More serious side effects, like pancreatitis or kidney problems, need medical treatment immediately. You should notify your physician if you develop lumps in your neck or throat area, difficulty swallowing, or hoarseness.

Editor’s Note: We would appreciate it if you could reach out to press@nowthendigital.com if you find any outdated or inaccurate content.

You’re reading nowthendigital.com — which breaks the news about Uganda, Kenya, Nigeria, South Africa and the rest of the world, day after day. Be sure to check out our homepage for all the latest news, and follow NOW THEN DIGITAL on YouTube, Google, Web Stories, Google News, Medium, LinkedIn, Twitter, Reddit, Pinterest, Linktr, Buy Me a Coffee, and Flipboard to stay in the loop.

Source: Now Then Digital
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Musasi Isaac

Musasi Isaac

A talented writer and blogger, Musasi Isaac Christopher specializes in the health, food, and restaurant categories at Now Then Digital and Lifestyle Uganda. WhatsApp on +256759100143.

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